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New developments in PD treatment.

Hi,
I’ve heard about a medication under development that is under trial to treat Parkinson’s Disease. It’s called Levodopa and is injected into the brain and is converted to Dopamine.
I read that Levodopa is combined is with Carbidopa (Lodosyn) which protects Levodopa from early conversion to Dopamine outside the brain. This prevents or lessens side effects such as nausea.

Any further information on this treatment would be appreciated.

  1. Thank you for your question, Apollo 18. Since I am not a doctor, I would suggest, if you haven't done so already, speak to your Movement Disorder Neurologist, who can tell you all about this new treatment. If you find out more information, kindly forward it to me. Regards, Marc M.
    Moderator, ParkinsonsDisease.Net

    1. I use Carbidopa-Levodopa, which is a PD med in pill form. I haven't heard about it being an injectable or that it's injected into the brain but I can say that I've been using Carbidopa-Levodopa since 2017 & it works wonderfully, or did for me. It lessened the tremors, ridigity & slowness in my gait. I'm happy with the med & haven't noticed any unwanted side effects. I hope that's helpful for u.

  2. Hi Marc, Thanks for your reply on my question on PD treatment. I will certainly keep you informed of any more info that comes my way. I'm not due to see my Neurologist until around the middle of November, but will certainly be asking those relative questions of him about this treatment. I have been proscribed medication being Madopar 125 which I note consists of 100mg of Levodoper as well as Benserazide 25 mg. to date I have resisted in commencing this medication as my Neurologist stated that it is not a cure but a symptom reliever. As my symptoms at this time are tolerable he suggested maintain the status quo until I decide to take it.
    It's been just over a year since I was diagnosed with PD. So far so good and I'm managing ok. Reflecting on PD, it's a significant factor that my brother died either from or with the effects of PD. He was 15 years older than me. I cannot imagine how we both acquired this disease as neither our mother or father who lived into their eighties, not my sister were afflicted with it.
    Regards,
    Max

    1. there is currently no cure, only treatment. I’d suggest trying this prescription, as honestly, what could go more wrong than the original diagnosis? If it doesn’t work, go back to what you were doing.
      I was diagnosed in February of 2018, and since then my levodopa has lost it’s effectiveness. I somehow got fast tracked into DBS, and the results have been life changing. In just a few short weeks I’m down to 1/4 of my meds, I’m sleeping better, and my normal energy levels have returned.

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