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Levodopa reaction

I’m a little jealous after reading so much about how Sinimet helps everybody. My neurologist has tried me on it & with increased carbodopa but I can’t tolerate it. She had started me on a reduced amount & very slowly & gradually increased it. And yes I always took it with food. I couldn’t get past 1/2 a tablet before it gave me a bad stomach ache & felt generally miserable. It would hit me about 2 hrs after taking it. That would go away in an hour or 2 but then it was time to take another one. She stopped that & put me on Rasagiline. ..with mixed reactions. I’ve always been cursed with an over reactive system to meds, supplements.
Anyway, it appears I have few options left other than DBS..tho I’m only in the early stages of PD. My symptoms are too much to deal with without some intervention.
Anyone else out there with similar problems?
Thanks, Laraine

  1. Laraine I share the same sensitivity to levadopa and cannot tolerate any dosage . I just began Regasiline and am hoping for positive results. I am not a candidate for DBS so I can only hope for the best.


    Team Member.

    1. I thought Rasagiline wasn’t going to work either but my 2nd try with it has been fine. It’s not helping any yet but I read that it could take a month or so before it starts working

      1. I was just reading a PD article about what good old fashioned exercise can do for increasing levels of dopamine in the brain. Pretty impressive photos..comparing exercise to medicine. I’m thinking of getting a stationary bike.

        1. You are so right about exercise.Due to severe osteoarthritis my exercise is limited. I do what I can to keep moving but the pain is difficult. Yesterday I had an ablation on the nerves in my right knee but only 2 of 3 could be done. My knees are so thin that the needles are all too big and would cause more damage than good, Wish me luck. Then I need to wait 8 weeks to see about the left. Thea

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