CommunityMemberdc68ab- as you may know amantadine is an old drug antiviral - not sure how works exactly but is used for chronic fatigue, and treatment for Parkinson’s since used in influenza pandemic and discovered that tremors and other Parkinson’s symptoms improved - especially tremors - also works well for treatment of motor fluctuations and dyskinesia’s - however in older patients may cause more confusion and short term memory loss - May cause severe sweating also in some people can cause depression and suicidal ideation which reverses when medicine is stopped - and long term use can cause a skin rash called livedo reticularis ( purplish lines in legs more common ) goes away w it’s stopping medication ‘hope this helps - Maria De Leon /author / moderator / patient advocate and leader