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About the medication Amantadine

I am wondering what experiences anyone has with the drug Amantadine (as a stand alone or combined with Levo/Carbo) - side effects, effectiveness of the drug. TY.

  1. In the early days when I was first diagnosed, I use amantadine. I found it effective. The biggest issue I had was the spiderweb rash livedo reticularis. It wasn't pretty, but it wasn't harmful. When it was really cold, I could see it more on my legs and arms. Eventually I stopped caring and just figured the medicine was more important than vanity. Here is an article I wrote here about it https://parkinsonsdisease.net/living/decisions good luck with your journey using it should you choose to go forward with it.

    1. CommunityMemberdc68ab- as you may know amantadine is an old drug antiviral - not sure how works exactly but is used for chronic fatigue, and treatment for Parkinson’s since used in influenza pandemic and discovered that tremors and other Parkinson’s symptoms improved - especially tremors - also works well for treatment of motor fluctuations and dyskinesia’s - however in older patients may cause more confusion and short term memory loss - May cause severe sweating also in some people can cause depression and suicidal ideation which reverses when medicine is stopped - and long term use can cause a skin rash called livedo reticularis ( purplish lines in legs more common ) goes away w it’s stopping medication ‘hope this helps - Maria De Leon /author / moderator / patient advocate and leader

      1. I have been using this medication for two months now together with Sinemet and believe it helps.
        But very slowly. Every day a little bit. Had lots of problems just walking a bit and the last couple of days have been making longer walks every day .

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