Hello, Just like , I'm not an expert but I do know that my father's neurologist recommended that he take his PD meds 1/2 hour before a meal so the protein in a meal wouldn't compete in your system with medication. We often have dad take his meds before he gets out of bed, in the morning, to kickstart his system and energy. Of course, we always recommend that you consult with your physician as we cannot give medical advice. I consider this a good tip. Best wishes, Suzanne Troy, ParkinsonsDisease.net Patient Leader