Hi All

Thanks for taking the time to share, Chris! It can certainly be difficult to navigate these symptoms. The resting tremor is typically associated with PD (as this article mentions: https://parkinsonsdisease.net/answers/differences-essential-tremor/), however, getting a proper diagnosis from a movement disorder specialist is the best course of action. If you need assistance in finding a movement disorder specialist near you, this article contains some online look-up tools: https://parkinsonsdisease.net/answers/find-a-movement-disorder-specialist/. Hope this information helps! - Chris, ParkinsonsDisease.net Team

Ok so i changed Docs (to my customer). Went for first visit last Monday, very thorough exam, he suspects PD early onset, prescribed 25mg of Carbidopa only as he wants to evaluate any changes before referring me to a Neurologist for treatment.

Im lost with this disease and what causes it , how it happens etc.

So i did my own research to try and figure it out as follows

So a person with Parkinson's means they are lacking in dopamine a neurotransmitter for the brain.

It could be not enough produced or that for some reason it's not getting past that boundary to the brain

For some reason the dopamine isn't getting to the brain where it's needed in the quantity needed therefore dopamine is required in more volume i.e. via Levodopa which is used as a dopamine replacement or it may just need help getting there via carbidopa

Levodopa is used as a dopamine replacement agent to boost the dopamine if there isn't enough naturally produced

Carbidopa (Lodosyn) is used to basically help the dopamine whether its naturally produced or derived from Levodopa get across the outer area boundary into the brain so it's not absorbed by the blood

So prescribing Carbidopa alone if there is enough naturally produced dopamine will help the brain absorb it rather than the blood. But if there isn't enough then you need Levodopa to boost it

If the above is true my question or thoughts why only prescribe Carbidopa that will only help the already naturally evolved dopamine get to where it should be, when if there isn't enough in qty you won't see any positive results anyway. Whereas if you were prescribed the carb/levodopa you would see results.

Or is it a case of trying to determine whether, is there enough dopamine being naturally produced and it just needs help getting to the brain with Carbidopa

In light of that are there 2 forms of Parkinson's

1. Where there is enough natural dopamine but just needs help getting to the brain

2. There isn't enough dopamine so its needs a boost and help getting to the brain

However in both cases the symptoms are the same because ultimately there is not enough dopamine getting to the brain

Thanks for sharing your story with us. I wish you all the best in your medical regimen / quest for knowledge / life in general.